TrkA-IN-3

Name: TrkA-IN-3
Brand: Adooq Bioscience
SKU: A34975
Rating: 5 (288 reviews)

Catalog No.: A34975

TrkA Inhibitor

TrkA-IN-3 is a potent allosteric inhibitor of TrkA, exhibiting an IC50 of 22.4 nM. It demonstrates over 8000-fold selectivity for TrkA compared to TrkB and TrkC, making it a valuable tool for targeted studies. This compound is applicable in pain research, aiding in the exploration of neurogenic pain mechanisms and potential therapeutic interventions.

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Grouped product items
Size	Price	Stock
5mg	$285.00	In stock
10mg	$505.00	In stock
25mg	$960.00	In stock
50mg	$1,220.00	In stock
100mg	$1,890.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	TrkA-IN-3 is a potent allosteric inhibitor of TrkA, exhibiting an IC50 of 22.4 nM. It demonstrates over 8000-fold selectivity for TrkA compared to TrkB and TrkC, making it a valuable tool for targeted studies. This compound is applicable in pain research, aiding in the exploration of neurogenic pain mechanisms and potential therapeutic interventions.

Product Information

Catalog Num	A34975
Formula	C24H17F3N4O3
Molecular Weight	466.41
CAS Number	3026111-73-6
SMILES	CN1C=CC(C2=CC(C(NC3=CC(C(O)=O)=CN=C3C4=CC=CC=C4)=O)=CC=C2C(F)(F)F)=N1

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