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TrkC-IN-1

TrkC Inhibitor

TrkC-IN-1 is a selective inhibitor of Tropomyosin receptor kinase C (TrkC), exhibiting IC50 values of 3.3-7.1 μM in EBC-1 cells and 7.3-10.2 μM in HT-29 cells. This compound demonstrates significant potential in cancer research, particularly in elucidating the role of TrkC in oncogenic signaling pathways. TrkC-IN-1 is a valuable tool for studying the therapeutic implications of targeting TrkC in various cancer types.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1877313-32-0
Applications	TrkC Inhibitor
Formula	C₂₈H₂₀BrN₅O₂
Molecular Weight	538.39
SMILES	BrC1=CC=C(CN2C3=CC=CC=C3C4(C2=O)C5=C(OC(N)=C4C#N)N(C6=CC=CC=C6)N=C5C)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.