Fig. 1 · Structure
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Troleandomycin
Cat. No.
A47733
CAS
2751-09-9
CYP3A Inhibitor
Troleandomycin, a macrolide antibiotic, functions as a selective inhibitor of the cytochrome P450 enzyme CYP3A. This compound is primarily used in research to investigate drug metabolism and interactions related to CYP3A. Additionally, it has applications in studies involving corticosteroids for conditions such as asthma, providing insights into therapeutic efficacy and safety profiles.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2751-09-9 |
| Applications | CYP3A Inhibitor |
| Formula | C41H67NO15 |
| Molecular Weight | 813.97 |
| Synonyms | Triacetyloleandomycin |
| SMILES | O=C1[C@@]2(C[C@@H]([C@@H]([C@H]([C@@H]([C@@H](C)C(O[C@H](C)[C@H](C)[C@@](OC(C)=O)([H])[C@H]1C)=O)O[C@@]3([H])C[C@@H]([C@@H](OC(C)=O)[C@H](C)O3)OC)C)O[C@@]4([H])[C@@H]([C@H](C[C@@H](C)O4)N(C)C)OC(C)=O)C)CO2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.