Fig. 1 · Structure

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Troriluzole

Glutamate Modulator

Troriluzole is an orally active glutamate modulator that functions as a third-generation proagent of Riluzole. It effectively reduces synaptic glutamate levels while enhancing glutamate absorption, making it a valuable candidate for the treatment of Alzheimer's disease and generalized anxiety disorder (GAD). Its unique mechanism of action underscores its potential in neurological research and therapeutic development.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1926203-09-9
Applications Glutamate Modulator
Formula C15H16F3N5O4S
Molecular Weight 419.38
Synonyms BHV-4157
SMILES
O=C(CN(C)C(CNC(CN)=O)=O)NC1=NC2=CC=C(OC(F)(F)F)C=C2S1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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