Fig. 1 · Structure

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TS-002266

TUT4/7 Inhibitor

TS-002266 is a selective inhibitor of the TUT4 and TUT7 enzymes, which play critical roles in RNA uridylation. This small molecule exhibits notable anti-leukemic properties, making it a valuable tool for cancer research. Its inhibition of TUT4/7 may provide insights into therapeutic strategies for hematological malignancies. Researchers can utilize TS-002266 to further understand the role of uridylation in cancer progression and treatment resistance.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2702325-64-0
Applications TUT4/7 Inhibitor
Formula C31H32Cl2N6O5
Molecular Weight 639.53
SMILES
COC1=C(C(OC[C@H]2CCCN2C3=C(C=C4C(C(C(O)=O)=CN(C4=C3)C5=CC=C(N=C5)N6CC(C6)N(C)C)=O)Cl)=NC=C1)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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