Fig. 1 · Structure

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TS-IN-7

TS Inhibitor

TS-IN-7 is a potent inhibitor of thymidylate synthase (TS), exhibiting an IC50 value of 39 nM. This compound is utilized in the research of cancer chemotherapy, providing valuable insights into the role of TS inhibition in therapeutic strategies against cancer. Its effectiveness makes it a critical tool for investigating the biochemical pathways associated with tumor growth and treatment response.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 150585-99-2
Applications TS Inhibitor
Formula C20H21N5O6
Molecular Weight 427.41
SMILES
CC(C1=CC=C(C=C1)C(N[C@H](C(O)=O)CCC(O)=O)=O)C2=CNC(NC(N)=N3)=C2C3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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