Fig. 1 · Structure
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TSHR antagonist S37b
TSHR Inhibitor
TSHR antagonist S37b is an enantiomeric compound that functions as a thyrotropin receptor (TSHR) inhibitor, exhibiting reduced efficacy compared to its counterpart, S37a. While S37b demonstrates a limited impact on TSHR inhibition, it serves as a valuable tool for investigations into thyroid function and dysregulation. This compound is suitable for research focused on the role of TSHR in thyroid-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2143452-22-4 |
| Applications | TSHR Inhibitor |
| Formula | C25H20N2O3S2 |
| Molecular Weight | 460.57 |
| SMILES | O=C(N1)SC([C@@H]2C3=CC=CC=C3)=C1S[C@]([C@]2([H])[C@]4([H])[C@]56[H])([H])[C@@](C4)([H])[C@@]6([H])C(N(C7=CC=CC=C7)C5=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.