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TT-62

Drug Derivative

TT-62 is an orally active derivative of FdUMP, functioning as an inhibitor of thymidylate synthase. This compound exhibits significant anti-cancer activity and is primarily utilized in cancer research to explore therapeutic pathways and potential treatment strategies. Its role in influencing pyrimidine metabolism makes it a valuable reagent for studying tumor response to chemotherapy and the underlying mechanisms of drug resistance.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	86976-77-4
Applications	Drug Derivative
Formula	C₂₃H₄₀FN₂O₈P
Molecular Weight	522.54
SMILES	O=C(N1)N([C@@H]2O[C@H](COP(OCCCCCCCCCCCCCC)(O)=O)[C@@H](O)C2)C=C(F)C1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.