Fig. 1 · Structure
Documents & Downloads
TTK inhibitor 3
Cat. No.
A55067
CAS
2820453-41-4
TTK Inhibitor
TTK Inhibitor 3 is a highly potent and selective inhibitor of TTK, a critical enzyme involved in the spindle assembly checkpoint. With an IC50 value of 3.0 nM, this compound effectively disrupts TTK activity, making it a valuable tool for studying cell cycle regulation and mitotic progression. Its application extends to research focused on cancer biology, particularly in the context of therapeutic approaches targeting aberrant cell division.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2820453-41-4 |
| Applications | TTK Inhibitor |
| Formula | C42H49N9O3 |
| Molecular Weight | 727.90 |
| SMILES | O=C1C2=CC(C3=C4C(NC=C4)=NC(NC5=CC=C(N6CCC(C(N7CC8(CN(C)C8)C7)=O)CC6)C=C5OC)=N3)=CN2CCN1C9=C(CC)C=CC=C9CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.