Fig. 1 · Structure
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TUG-424
Free Fatty Acid Receptor Agonist
TUG-424 is a selective agonist for the free fatty acid receptor 1 (FFA1/GPR40) with an EC50 of 32 nM. It significantly enhances glucose-stimulated insulin secretion at concentrations of 100 nM, making it a valuable tool for investigating the role of FFA1 in metabolic disorders such as diabetes and obesity. Additionally, TUG-424 contains an alkyne group and can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating its use in click chemistry applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1082058-99-8 |
| Applications | Free Fatty Acid Receptor Agonist |
| Formula | C18H16O2 |
| Molecular Weight | 264.32 |
| SMILES | OC(CCC(C=C1)=CC=C1C#CC2=C(C)C=CC=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.