Fig. 1 · Structure
Documents & Downloads
TUG-469
FFA1 Agonist
TUG-469 is a selective agonist of the free fatty acid receptor 1 (FFA1/GPR40) with an EC50 value of 19 nM, demonstrating over 200-fold selectivity for FFA1 compared to FFA4. This compound has been shown to significantly enhance glucose tolerance in pre-diabetic mouse models. TUG-469 serves as a valuable tool for research into diabetes and metabolic disorders, advancing the understanding of FFA1 signaling in glucose homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1236109-67-3 |
| Applications | FFA1 Agonist |
| Formula | C23H23NO2 |
| Molecular Weight | 345.43 |
| SMILES | O=C(CCC1=CC=C(C=C1)NCC2=CC(C3=CC=CC=C3C)=CC=C2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.