TUG-499 is a selective agonist of the free fatty acid receptor 1 (FFAR1 or GPR40), showcasing a pEC50 of 7.39. This compound demonstrates over 100-fold selectivity against related receptors, including FFA2, FFA3, and PPARγ, as well as other receptors, ion channels, and transporters. TUG-499 serves as a valuable tool in the investigation of type 2 diabetes and features an alkyne group, enabling its use in click chemistry applications through copper-catalyzed azide-alkyne cycloaddition (CuAAc).
TUG-499 is a selective agonist of the free fatty acid receptor 1 (FFAR1 or GPR40), showcasing a pEC50 of 7.39. This compound demonstrates over 100-fold selectivity against related receptors, including FFA2, FFA3, and PPARγ, as well as other receptors, ion channels, and transporters. TUG-499 serves as a valuable tool in the investigation of type 2 diabetes and features an alkyne group, enabling its use in click chemistry applications through copper-catalyzed azide-alkyne cycloaddition (CuAAc).
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
