Fig. 1 · Structure
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TWS119 TFA
Small Molecules Kinase
TWS119 TFA is a selective inhibitor of glycogen synthase kinase 3 beta (GSK-3β), exhibiting an IC50 of 30 nM. This compound is known to activate the Wnt/β-catenin signaling pathway, making it a valuable tool for research in cell signaling, development, and cancer biology. Its specificity and potency enhance its utility in studies focused on GSK-3β-related pathways and their implications in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1507095-58-0 |
| Applications | Small Molecules Kinase |
| Formula | C22H16F6N4O6 |
| Molecular Weight | 546.38 |
| SMILES | OC1=CC=CC(OC2=C3C(NC(C4=CC=CC(N)=C4)=C3)=NC=N2)=C1.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.