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TX2-120-1

Her3 Degrader

TX2-120-1 is a potent Her3 degrader, exhibiting an IC50 value of 56 nM for Her3 binding. This compound facilitates the degradation of the Her3 protein, making it a valuable tool for investigating Her3-related pathways and therapeutic applications. Additionally, TX2-120-1 can be utilized in the synthesis of TX2-121-1, further expanding research possibilities in targeted protein degradation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	1603845-45-9
Applications	Her3 Degrader
Formula	C₂₆H₂₇N₇O₂
Molecular Weight	469.54
SMILES	CN1CCC(N2C3=NC=NC(N)=C3C(C(C=C4)=CC(NC(C=C)=O)=C4OC5=CC=CC=C5)=N2)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.