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Tyk2-IN-18-d3

Tyk2 Inhibitor

Tyk2-IN-18-d3 is a potent Tyk2 inhibitor with an IC50 value of less than 30 nM for both IL-23 and IFNα. This selective inhibition of Tyk2 makes it a valuable tool for investigating the signaling pathways involved in autoimmune diseases. Its ability to modulate Tyk2 activity provides insights into potential therapeutic strategies for conditions driven by dysregulated immune responses.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3018160-68-1
Applications	Tyk2 Inhibitor
Formula	C₂₃H₂₃D₃N₈O₂
Molecular Weight	449.52
SMILES	C[C@@H]1C(C(C2=CC=NC(NC3=CC(NC(C4CC4)=O)=NC=C3C(CC([2H])([2H])[2H])=O)=C2N1C)=N5)=NN5C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.