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TyK2-IN-21-d3

TyK2 Inhibitor Prodrug

TyK2-IN-21-d3 is a prodrug of tyrosine kinase 2 (TyK2) designed for oral administration. It demonstrates excellent chemical stability across varying pH levels, which enhances its bioavailability by mitigating the impact of gastric acid fluctuations on drug absorption. This compound is valuable for research applications targeting TyK2-related pathways in diseases where modulation of this kinase may provide therapeutic benefits.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2583719-08-6
Applications	TyK2 Inhibitor Prodrug
Formula	C₂₁H₂₂D₃N₈O₇P
Molecular Weight	535.46
SMILES	O=P(O)(OCN1C=C(C(NC([2H])([2H])[2H])=O)C(NC2=CC=CC(C3=NN(C)N=N3)=C2OC)=C/C1=N\C(C4CC4)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.