Tyk2-IN-8

Name: Tyk2-IN-8
SKU: A19052
Price: 320 USD
Rating: 5 (288 reviews)

Catalog No.: A19052

TYK2 inhibitor

Tyk2-IN-8 (compound 10) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain with an IC50 of 17 nM, used in the treatment of psoriasis.

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Grouped product items
Product Name	Price	Stock
Tyk2-IN-8 1mg	$320.00	In stock
Tyk2-IN-8 5mg	$960.00	In stock
Tyk2-IN-8 10mg	$1,600.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Biological Activity

Discription	Tyk2-IN-8 (compound 10) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain with an IC50 of 17 nM, used in the treatment of psoriasis.

Product Information

Catalog Num	A19052
Formula	C20H17N9
Molecular Weight	383.41
CAS Number	2127109-84-4
SMILES	N#CC[C@@]1(N2N=CC(C3=NC(C4=CN(C)N=C4)=CN5C3=CC=N5)=C2)C[C@H](C#N)C1
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	72 mg/mL (187.78 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.08 mL	130.41 mL	260.82 mL
0.5 mM	5.22 mL	26.08 mL	52.16 mL
1 mM	2.61 mL	13.04 mL	26.08 mL
5 mM	0.52 mL	2.61 mL	5.22 mL

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