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TYK2 JH2-IN-1-d3

TYK2 Inhibitor

TYK2 JH2-IN-1-d3 is a deuterated, orally active inhibitor targeting the JH2 domain of TYK2 with an IC50 of 0.1 nM. This selective TYK2 inhibitor is valuable for investigating the biological roles of TYK2 in signaling pathways related to various diseases, including autoimmune disorders. It serves as an essential tool for both in vitro and in vivo research applications focused on TYK2-mediated processes.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2376999-19-6
Applications	TYK2 Inhibitor
Formula	C₂₄H₂₁D₃FN₉O₃
Molecular Weight	508.52
SMILES	FC1=CN=C(C2=C(OC)C(NC3=C(C(NC([2H])([2H])[2H])=O)N=NC(NC4=NC=C(C(C)(C)O)C=C4)=C3)=NC=C2)N=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.