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TYK2 ligand 1

TYK2 Ligand

TYK2 Ligand 1 is a specific ligand for the Janus kinase TYK2, implicated in the development of PROTAC-based degrader molecules, particularly CPD-155. This compound showcases significant potential in drug discovery research aimed at regulating TYK2 activity through targeted protein degradation. It is valuable for studies focused on autoimmune diseases and inflammatory disorders where TYK2 plays a crucial role in cytokine signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2770471-05-9
Applications	TYK2 Ligand
Formula	C₂₂H₂₁N₉O₄
Molecular Weight	475.46
SMILES	O=C(C1=CN=C(NC2=NN=C(C(NC3=CC=CC(C4=NN(C)C=N4)=C3OC)=C2)C(NC)=O)C=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.