Fig. 1 · Structure

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TYK2 ligand 4

TYK2 Ligand

TYK2 Ligand 4 is a selective ligand for TYK2, targeting both the kinase and pseudokinase domains. By inducing an inactive conformation of the kinase domain, it effectively inhibits ATP binding, thereby modulating TYK2 activity. This compound is valuable for research applications aimed at developing therapeutics such as Deucravacitinib, contributing to the understanding of TYK2's role in various inflammatory and autoimmune diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 1258295-27-0
Applications TYK2 Ligand
Formula C16H14ClN3O2
Molecular Weight 315.75
SMILES
O=C(NC1=CC(NC(C2CC2)=O)=NC=C1)C3=CC=CC=C3Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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