Fig. 1 · Structure

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(+)-Tyrphostin B44

EGRF Inhibitor

(+)-Tyrphostin B44 is an Epidermal Growth Factor Receptor (EGFR) inhibitor known for its antitumor properties. This compound exhibits significant biological activity in inhibiting EGFR signaling pathways, which are critical in cellular proliferation and survival. It has applications in cancer research, particularly in studying the effects of EGFR inhibition on tumor growth and progression.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 133550-37-5
Applications EGRF Inhibitor
Formula C18H16N2O3
Molecular Weight 308.33
Synonyms Tyrphostin AG 835; Tyrphostin B 50
SMILES
O=C(N[C@H](C1=CC=CC=C1)C)/C(C#N)=C/C2=CC=C(O)C(O)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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