U-101958 maleate is a highly selective antagonist for the dopamine D4 receptor, exhibiting an IC50 of 2.7 nM. In HEK-293 cells expressing the human recombinant D4.4 receptor, U-101958 behaves as an agonist, demonstrating its versatile interaction with this target. This compound is primarily utilized in research related to antipsychotic effects and the modulation of dopaminergic signaling pathways.
U-101958 maleate is a highly selective antagonist for the dopamine D4 receptor, exhibiting an IC50 of 2.7 nM. In HEK-293 cells expressing the human recombinant D4.4 receptor, U-101958 behaves as an agonist, demonstrating its versatile interaction with this target. This compound is primarily utilized in research related to antipsychotic effects and the modulation of dopaminergic signaling pathways.
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