Fig. 1 · Structure

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(±)-U-50488 hydrochloride ((±)-Trans-(1R,2R)-U-50488)

KOR Agonist

(±)-U-50488 hydrochloride is a selective agonist of the κ opioid receptor (KOR). It exhibits significant analgesic and anti-inflammatory properties, making it valuable for studies related to pain management and opioid receptor signaling pathways. This compound is ideal for research applications investigating the role of KOR in various physiological processes and potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 67197-96-0
Applications KOR Agonist
Formula C19H27Cl3N2O
Molecular Weight 405.79
Synonyms (±)-Trans-(1R,2R)-U-50488 hydrochloride; (±)-Trans-(1R,2R)-U-50488
SMILES
O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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