Fig. 1 · Structure
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UBA5-IN-1
UBA5 Inhibitor
UBA5-IN-1 is a selective inhibitor of UBA5, exhibiting an IC50 value of 4.0 μM. This compound effectively inhibits the proliferation of Sk-Luci6 cancer cells, which are characterized by elevated UBA5 expression levels. UBA5-IN-1 is useful in studies exploring the roles of UBA5 in cancer biology and offers potential insights for therapeutic strategies targeting UBA5-related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1831169-11-9 |
| Applications | UBA5 Inhibitor |
| Formula | C26H40F6N10O11S2Zn |
| Molecular Weight | 912.16 |
| SMILES | O=S(C(F)(F)F)([O-])=O.O=S(C(F)(F)F)([O-])=O.NC1=C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](C(NCCCCCC([N]45[Zn+2]67[N@@](CC[N]6([H])CC[N@]7([H])CC5)([H])CC4)=O)=O)O3)C2=NC=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.