Fig. 1 · Structure

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UBE2T/FANCL-IN-1

Fanconi Anemi Pathway Inhibitor

UBE2T/FANCL-IN-1 is a potent inhibitor of the UBE2T/FANCL-mediated pathway, specifically targeting FANCD2 monoubiquitylation. By interfering with this critical process, it sensitizes cells to DNA cross-linking agents such as Carboplatin. This compound is valuable for research focused on understanding the mechanisms of Fanconi anemia and evaluating therapeutic strategies for genomic instability and cancer treatment.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1359415-02-3
Applications Fanconi Anemi Pathway Inhibitor
Formula C19H31N7
Molecular Weight 357.50
SMILES
CC(CCCC1)N1CC2=NN3C(N4CCN(CC)CC4)=CC(C)=NC3=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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