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UBP 1112

Group III mGluR Antagonist

UBP 1112 is a selective antagonist of group III metabotropic glutamate receptors (mGluRs), demonstrating a dissociation constant (Kd) of 5.1 μM. This compound exhibits a 96-fold preference for group III mGluRs over group II receptors, with a Kd value of 488 μM for the latter. UBP 1112 does not display significant activity at group I mGluRs or ionotropic glutamate receptors (iGluRs). This specificity positions UBP 1112 as a valuable tool for studying the physiological and pathological roles of group III mGluRs in various neurological research applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	339526-74-8
Applications	Group III mGluR Antagonist
Formula	C₁₀H₁₄NO₅P
Molecular Weight	259.20
SMILES	OC(C(N)(C1=CC(C)=C(P(O)(O)=O)C=C1)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.