Fig. 1 · Structure
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UBP 302
iGluR Antagonist
UBP 302 is a potent and selective antagonist of the GLUK5 subunit-containing kainate receptors, exhibiting an apparent Kd value of 402 nM. It shows minimal affinity for GluK2 (GluR6) kainate receptors, making it an invaluable tool for differentiating between these receptor subtypes. UBP 302 has demonstrated anxiolytic effects, contributing to its potential applications in neuroscience research focused on anxiety and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 745055-91-8 |
| Applications | iGluR Antagonist |
| Formula | C15H15N3O6 |
| Molecular Weight | 333.30 |
| SMILES | O=C(N(C=CC1=O)C[C@H](N)C(O)=O)N1CC2=C(C=CC=C2)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.