Fig. 1 · Structure
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UBP141
GluN2C/2D Antagonist
UBP141 is a selective antagonist of the GluN2C and GluN2D NMDA receptor subtypes, exhibiting Kd values of 2.8 μM, 4.2 μM, 14.2 μM, and 19.3 μM for GluN2C, GluN2D, GluN2A, and GluN2B, respectively. This compound demonstrates significant motor impairment in wild-type mice, highlighting its potential role in studies related to motor function and NMDA receptor dynamics. UBP141 is valuable for research investigating neurological disorders and receptor-specific signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 344768-30-5 |
| Applications | GluN2C/2D Antagonist |
| Formula | C21H18N2O5 |
| Molecular Weight | 378.38 |
| SMILES | O=C(O)[C@@H]1N(CCN[C@@H]1C(O)=O)C(C2=CC=C3C=CC4=CC=CC=C4C3=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.