Fig. 1 · Structure
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UBP301
Kainate Receptor Antagonist
UBP301 is a selective antagonist of kainate receptors, exhibiting an IC50 of 164 μM and a KD of 5.94 μM. With approximately 30-fold selectivity for kainate receptors over AMPA receptors, UBP301 can serve as a valuable tool in investigating synaptic transmission and neuropharmacology. This compound is useful for studies aimed at elucidating the roles of kainate receptors in various neurobiological processes and potential therapeutic applications in neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 569371-10-4 |
| Applications | Kainate Receptor Antagonist |
| Formula | C15H14IN3O6 |
| Molecular Weight | 459.19 |
| SMILES | O=C(N(C=C(I)C1=O)C[C@H](N)C(O)=O)N1CC2=CC=C(C(O)=O)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.