Fig. 1 · Structure
Documents & Downloads
UBP316
GluK1/GluR5 Antagonist
UBP316 is a highly potent and selective antagonist of the kainate receptors GluK1 and GluR5, exhibiting a Kb value of 1.4 nM. This compound effectively inhibits the depression of field excitatory postsynaptic potentials (fEPSPs) and GABAergic transmission induced by the GluK1 selective agonist ATPA. UBP316 is valuable for research applications involving synaptic transmission modulation and investigating the role of kainate receptors in neurological studies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 936095-50-0 |
| Applications | GluK1/GluR5 Antagonist |
| Formula | C20H19N3O6S |
| Molecular Weight | 429.45 |
| Synonyms | ACET |
| SMILES | OC(C(SC(C1=CC=CC=C1)=C2)=C2CN3C(N(C=C(C)C3=O)C[C@H](N)C(O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.