Fig. 1 · Structure
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UBX1325
Bcl-xL Inhibitor
UBX1325 is a selective Bcl-xL inhibitor that facilitates apoptosis in senescent cells. This compound is a significant tool for investigating age-related biological processes and is particularly relevant in research on age-related eye diseases, including diabetic macular edema (DME), age-related macular degeneration (AMD), and diabetic retinopathy (DR). Its potent pro-apoptotic activity makes UBX1325 valuable for studies focused on anti-aging interventions and associated cellular mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2271269-01-1 |
| Applications | Bcl-xL Inhibitor |
| Formula | C53H59ClF3N6O10PS3 |
| Molecular Weight | 1159.69 |
| SMILES | CC1=C(C(C2=CC=CC(N3CCN(CC3)C4=CC=C(C=C4)NS(=O)(C5=CC=C(C(S(=O)(C(F)(F)F)=O)=C5)N[C@@H](CSC6=CC=CC=C6)CCN7CCC(CC7)OP(O)(O)=O)=O)=C2)=C(N1C(C)C)C8=CC=C(C=C8)Cl)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.