Fig. 1 · Structure

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UC2288

P21 Attenuator

UC2288 is a potent orally active p21 attenuator, primarily targeting the p21 pathway with relative selectivity. This compound effectively inhibits cancer cell proliferation by inducing apoptosis. Notably, UC2288 does not inhibit VEGFR2 or Raf kinases, even at concentrations up to 10 μM, making it a valuable tool for studying p21-related signaling pathways in cancer research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1394011-91-6
Applications P21 Attenuator
Formula C20H18ClF6N3O2
Molecular Weight 481.82
SMILES
O=C(N[C@H]1CC[C@H](OC2=NC=C(C(F)(F)F)C=C2)CC1)NC3=CC=C(Cl)C(C(F)(F)F)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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