Fig. 1 · Structure
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UCB-J
SV2A Ligand
UCB-J is a selective ligand for synaptic vesicle protein 2A (SV2A), exhibiting pIC50 values of 8.15 for human SV2A and 7.6 for rat SV2A. This compound facilitates the visualization and quantification of total synaptic density across various brain regions, making it a valuable tool for studying synaptic function and integrity. UCB-J is particularly useful in research applications focused on neurological disorders and synaptic transmission.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2242957-52-2 |
| Applications | SV2A Ligand |
| Formula | C17H15F3N2O |
| Molecular Weight | 320.31 |
| SMILES | O=C1C[C@@](C2=CC(F)=C(C(F)=C2)F)([H])CN1CC3=CC=NC=C3C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.