Documents & Downloads

UCB1244283

SV2A Allosteric Modulator

UCB1244283 is an allosteric modulator of synaptic vesicle glycoprotein 2A (SV2A). It binds to a secondary site on SV2A, enhancing the engagement of orthosteric ligands by stabilizing the occluded state and reducing ligand dissociation. This compound exhibits a protective effect against tonic and clonic convulsions in sound-sensitive mice, making it valuable for research in epilepsy and related neurological disorders.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	300587-89-7
Applications	SV2A Allosteric Modulator
Formula	C₂₀H₂₅NO₂
Molecular Weight	311.42
SMILES	O=C(NC1=CC=CC=C1OC)CC(C)CC2=CC(C)=CC(C)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.