UCCF-853

Catalog No.: A66481
CFTR Modulator
UCCF-853 is a CFTR modulator that targets the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, enhancing its chloride ion channel activity. This compound has demonstrated the ability to improve epithelial ion transport, making it a valuable tool for research into therapies for cystic fibrosis and related disorders. UCCF-853 is essential for studying the modulation of CFTR function and potential rescue of defective CFTR variants in cellular models.
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
2mg
$35.00
In stock
5mg
$60.00
In stock
10mg
$95.00
In stock
25mg
$160.00
In stock
50mg
$230.00
In stock
100mg
$335.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionUCCF-853 is a CFTR modulator that targets the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, enhancing its chloride ion channel activity. This compound has demonstrated the ability to improve epithelial ion transport, making it a valuable tool for research into therapies for cystic fibrosis and related disorders. UCCF-853 is essential for studying the modulation of CFTR function and potential rescue of defective CFTR variants in cellular models.
Product Information
Catalog NumA66481
FormulaC14H8ClF3N2O
Molecular Weight312.67
CAS Number625458-06-2
SMILESO=C1N(C2=CC=C(C=C2N1)C(F)(F)F)C3=CC=CC(Cl)=C3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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