Fig. 1 · Structure
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UCK2 Inhibitor-2
UCK2 Inhibitor
UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with an IC50 of 3.8 µM. This compound effectively suppresses uridine salvage pathways in cells, making it a valuable tool for studying nucleotide metabolism and cell proliferation. Its ability to modulate UCK2 activity underlines its potential in research focused on cancer biology and other diseases associated with aberrant nucleotide recycling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 866842-71-9 |
| Applications | UCK2 Inhibitor |
| Formula | C28H23N3O4S |
| Molecular Weight | 497.56 |
| SMILES | O=C(C1=CC(NC(CSC2=C3CC4=C(C(C)=CC=C4)OC3=NC(C5=CC=C(C)C=C5)=N2)=O)=CC=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.