UCSF678 is a 5-HT5A receptor agonist exhibiting a partial agonist profile with an affinity of 42 nM. This compound demonstrates arrestin-biased signaling, providing a more focused exploration of the 5-HT5AR pathway with fewer off-target effects and reduced assay-related issues. UCSF678 serves as a valuable tool for investigating the physiological roles and functional dynamics of the 5-HT5A receptor in various research applications.
UCSF678 is a 5-HT5A receptor agonist exhibiting a partial agonist profile with an affinity of 42 nM. This compound demonstrates arrestin-biased signaling, providing a more focused exploration of the 5-HT5AR pathway with fewer off-target effects and reduced assay-related issues. UCSF678 serves as a valuable tool for investigating the physiological roles and functional dynamics of the 5-HT5A receptor in various research applications.
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