Fig. 1 · Structure
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UFP-512
DOP Receptor Agonist
UFP-512 is a selective and potent agonist of the δ-opioid receptor (DOP receptor). It demonstrates significant antidepressant and anxiolytic properties by effectively inhibiting adenylyl cyclase activity and activating Erk1/2 pathways. UFP-512 promotes the phosphorylation of DOP receptors at Ser363 while exhibiting minimal desensitization of the cAMP pathway. This compound is a valuable tool for investigating mood disorders and related therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 480446-44-4 |
| Applications | DOP Receptor Agonist |
| Formula | C31H33N5O5 |
| Molecular Weight | 555.62 |
| SMILES | CC(C=C(C=C1C)O)=C1C[C@H](N)C(N2[C@@H](CC3=CC=CC=C3C2)C(N[C@H](C4=NC5=CC=CC=C5N4)CC(O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.