Fig. 1 · Structure
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UGT8-IN-1
UGT8 Inhibitor
UGT8-IN-1 is a potent inhibitor of the enzyme ceramide galactosyltransferase (UGT8), demonstrating the ability to penetrate the blood-brain barrier and exhibit oral bioactivity. This compound is valuable for research applications focused on lysosomal storage disorders, providing insights into the pathophysiology of these conditions and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2414349-93-0 |
| Applications | UGT8 Inhibitor |
| Formula | C20H22F6N4O4S |
| Molecular Weight | 528.47 |
| SMILES | O=C(OC1CCN(C2=CC(C(F)(F)F)=C3C(C(C(NC)=O)=CS3)=N2)CC1)N[C@@H](C)COC(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.