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UHMCP1 dihydrochloride

UHM Domain Inhibitor

UHMCP1 dihydrochloride is a potent inhibitor of the UHM domain, exhibiting a Kd value of 79 μM. This compound effectively disrupts the interaction between SF3b155 and U2AF65, leading to alterations in RNA splicing. UHMCP1 dihydrochloride may also influence cell viability, making it an important tool for research into splicing mechanisms and associated cellular processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2925647-93-2
Applications	UHM Domain Inhibitor
Formula	C₁₉H₂₉Cl₂N₃
Molecular Weight	370.36
SMILES	CC(N(C[C@]1([H])CC2)C[C@]2([H])[C@H]1N)CCC3=CNC4=CC=CC=C34.[H]Cl.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.