Fig. 1 · Structure
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UK‑396082
TAFI Inhibitor
UK-396082 is a potent inhibitor of thrombin-activated fibrinolytic inhibitor (TAFI), known for its ability to enhance plasmin activity while concurrently reducing extracellular matrix (ECM) levels. This compound is primarily utilized in research investigating chronic kidney disease (CKD) and its associated pathophysiological processes. Its distinct mechanism supports studies focused on fibrinolysis and its implications in renal health and disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 400044-47-5 |
| Applications | TAFI Inhibitor |
| Formula | C12H21N3O2 |
| Molecular Weight | 239.31 |
| SMILES | CCCN1C=C(C[C@@H](C(O)=O)CCCN)N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.