ULK1-IN-2 is a potent inhibitor of ULK1, a key regulator of autophagy. This compound exhibits significant cytotoxic effects against cancer cell lines, demonstrating an IC50 of 1.94 μM in A549 cells. ULK1-IN-2 not only induces apoptosis but also effectively inhibits autophagy, making it a valuable tool for research applications in non-small cell lung cancer (NSCLC) studies.
ULK1-IN-2 is a potent inhibitor of ULK1, a key regulator of autophagy. This compound exhibits significant cytotoxic effects against cancer cell lines, demonstrating an IC50 of 1.94 μM in A549 cells. ULK1-IN-2 not only induces apoptosis but also effectively inhibits autophagy, making it a valuable tool for research applications in non-small cell lung cancer (NSCLC) studies.
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