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Biological Activity
Umbralisib R-enantiomer (TGR-1202 R-enantiomer) is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.5 mL | 87.48 mL | 174.96 mL |
| 0.5 mM | 3.5 mL | 17.5 mL | 34.99 mL |
| 1 mM | 1.75 mL | 8.75 mL | 17.5 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.5 mL |
*The above data is based on the productmolecular weight 571.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21993 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1532533-69-9 |
| Formula | C31H24F3N5O3 |
| M. Wt | 571.55 |
| Purity | >98% |
| Synonyms | TGR-1202 R-enantiomer, TGR1202, TGR 1202; RP5264 R-enantiomer, RP 5264, RP-5264 |
| SMILES | O=C1C(C2=CC=CC(F)=C2)=C([C@@H](C)N3N=C(C4=CC=C(OC(C)C)C(F)=C4)C5=C(N)N=CN=C53)OC6=CC=C(F)C=C16 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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