Fig. 1 · Structure
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UMK57
UMK57 is a small molecule that promotes the correction of kinetochore-microtubule (k-MT) attachment errors, thereby inhibiting chromosome missegregation. This compound enhances the fidelity of chromosome segregation by destabilizing k-MT attachments during mitosis. UMK57 is particularly relevant for research focused on mitotic regulation and the mechanisms underlying chromosomal instability.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 342595-74-8 |
| Formula | C17H17N3S |
| Molecular Weight | 295.40 |
| SMILES | CC1=CC=C(C=C1)C2=CSC3=NC=NC(N4CCCC4)=C32 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.