Fig. 1 · Structure
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UNC-CA2-103
TLK2 Inhibitor
UNC-CA2-103 is a selective inhibitor of TLK2, exhibiting a human IC50 of 18 nM. It demonstrates high specificity for TLK2 over TLK1 and most other kinases, making it a valuable tool for targeted research. This compound is particularly relevant in studies related to breast cancer, glioblastoma, and gastric cancer, facilitating investigations into the role of TLK2 in these malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3069333-33-8 |
| Applications | TLK2 Inhibitor |
| Formula | C20H16N4O2 |
| Molecular Weight | 344.37 |
| SMILES | O=C(NC1=CC2=C(NC(/C2=C\C3=C(C)N=CN3)=O)C=C1)C4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.