Fig. 1 · Structure
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UNC10142
CHD1 Antagonist
UNC10142 is a selective antagonist of CHD1, exhibiting an IC50 value of 1.7 μM. This small molecule induces dose-dependent cytotoxicity in PTEN-deficient prostate cancer cells, highlighting its potential utility in cancer research. UNC10142 serves as a valuable tool for investigating the role of CHD1 in cancer biology and for exploring therapeutic strategies targeting this pathway.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 3118919-69-7 |
| Applications | CHD1 Antagonist |
| Formula | C33H52N6O3 |
| Molecular Weight | 580.80 |
| SMILES | COC1=C(OCCCN2CCCCC2)C=C(N=C(N3CCCCCCCC3)N=C4N(C)C5CCN(C(C)=O)CC5)C4=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.