UNC569

Catalog No.: A13805

Mer Inhibitor

UNC569

UNC569 Chemical Structure

CAS NO. 1350547-65-7

UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. UNC569 is the first small-molecule Mer inhibitor. UNC569 inhibited Mer activation and downstream signaling through ERK1/2 and AKT.

Availability: In stock

Package Price Qty
10 mg
$150.00
25 mg
$300.00
50 mg
$500.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

UNC569 is a novel small-molecule MER inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivo. UNC569 is the first small-molecule Mer inhibitor. UNC569 inhibited Mer activation and downstream signaling through ERK1/2 and AKT.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.22 mL 126.1 mL 252.21 mL
0.5 mM 5.04 mL 25.22 mL 50.44 mL
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL

*The above data is based on the productmolecular weight 396.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13805
Actions Inhibitor
M. Wt 396.5
Formula C22H29FN6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1350547-65-7
Synonyms UNC-569, UNC 569
SMILES CCCCNC1=NC=C2C(=NN(C2=N1)CC3CCC(CC3)N)C4=CC=C(C=C4)F

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