Fig. 1 · Structure
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UNC7437
IPMK Inhibitor
UNC7437 is an inhibitor of inositol phosphate multikinase (IPMK), demonstrating an IC50 value of 26.2 nM. This compound exhibits notable anti-proliferative effects on glioblastoma cells and significantly reduces the accumulation of inositol phosphates InsP4, InsP5, and InsP6 within cellular environments. UNC7437 is applicable for research focusing on TEN-negative glioblastoma models, providing a valuable tool for studying the mechanistic role of IPMK in cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2967647-41-0 |
| Applications | IPMK Inhibitor |
| Formula | C18H15NO3 |
| Molecular Weight | 293.32 |
| SMILES | O=C(O)/C=C/C1=CC2=C(C3=CC(C)=CC(C)=C3)ON=C2C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.