Fig. 1 · Structure

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UNC8732 TFA

Promote Protein Degrader

UNC8732 (TFA) is a potent inhibitor of NSD2, functioning as a protein degrader. This compound promotes cellular degradation of NSD2, which plays a critical role in various cellular processes, including gene expression and chromatin regulation. UNC8732 (TFA) is utilized in research related to cancer biology and epigenetic regulation, providing insights into NSD2's role in disease mechanisms and potential therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2929304-06-1
Applications Promote Protein Degrader
Formula C37H40F3N5O7
Molecular Weight 723.74
SMILES
O=C(C(F)(F)F)O.O=C(C1=CC=C(CN(C2CC2)C(C3=CC=C4NC(COC4=C3)=O)=O)C=C1)NC5=CC=C6C(CCN(C6)C(CCCCCN)=O)=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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