Fig. 1 · Structure
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Unguinol
Depsilic Acid
Unguinol is a depsidone that functions as an inhibitor of pyruvate phosphate dikinase (PPDK), with an IC50 value of 42.3 μM. It exhibits selective inhibition on the growth of plants employing C4 carbon fixation while sparing those utilizing C3 pathways. Additionally, Unguinol demonstrates antimicrobial activity against Staphylococcus aureus and Vibrio harveyi, with GI50 values of 8.7 μM and 69.5 μM, respectively. This compound also shows cytotoxic effects on cancer cell lines H460, MCF-7, and SF-268, with GI50 values of 28.2 μM, 50.8 μM, and 44.3 μM, respectively, making it a valuable tool in cancer research and plant biology studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 36587-59-4 |
| Applications | Depsilic Acid |
| Formula | C19H18O5 |
| Molecular Weight | 326.34 |
| SMILES | CC1=C2C(OC3=C(C(O2)=O)C(C)=CC(O)=C3)=C(C=C1O)/C(C)=C/C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.